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Antioxidant strategies to prevent eye disease: is the lens a glutathione reservoir?

60 months
Approved budget:
Dr Julie Lim
Health issue:
Proposal type:
Sir Charles Hercus Fellowship
Lay summary
We will investigate whether the lens supplies other tissues in the eye with protective antioxidants. This implies that lens removal during cataract surgery may inadvertently deplete antioxidants in the eye, exposing it to oxidative stress. Supplementation of antioxidants after cataract surgery may therefore be required to restore these levels and protect the eye from diseases that may result in loss of sight.