There are significant inequalities in cancer survival between Maori and non-Maori, and evidence that comorbidity (the presence of other health problems) and service access play important roles. This research aims to understand the independent and interacting influences of ethnicity and comorbidity on cancer survival and to develop interventions that will change health delivery to reduce these inequalities. Methods include; recording of multidisciplinary team meetings, 'digital diaries' of patient and clinician perceptions of consultations, and interviews with patients about their cancer journey. Maori community and clinical oversight groups will provide research guidance. Outcomes include improved understanding of ethnicity and comorbidty on clinical decision-making about cancer treatment, and cancer journeys, and the development, piloting and evaluation of at least three interventions to reduce these inequalities. This research has the potential to improve the management of cancer and comorbidity in Maori, and possibly the management of other chronic diseases.