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Neural control of fertility

64 months
Approved budget:
Professor Allan Herbison
Health issue:
Reproduction/fertility/sexual health
Proposal type:
Lay summary
This programme of work will determine how a specific network of brain cells controls fertility. Using a variety of different mouse models and state-of-the-art neuroscience techniques, the three principal investigators leading this programme will examine how this network functions to generate the cyclical nature of fertility in females. Previous studies in these exact same mouse models have proven to be very effective in generating promising new therapies for the beneficial regulation of fertility in humans. A full understanding of how this network functions normally will provide the foundations for designing new therapies to help infertile couples and safer, more effective, contraceptives.