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Is there a ‘fourth axis’ of vesicular communication?

49 months
Approved budget:
Professor Anthony Phillips
Health issue:
Infectious disease
Proposal type:
Explorer Grant
Lay summary
Human cells in our body communicate with one another through multiple pathways. One established route is via their ability to produce a range of different signalling “packages”, called vesicles. These packages can travel between our cells and around our body delivering a range of chemical messages. Here we propose a new function for these vesicles that provides a novel communication activity and axis. This axis is likely to underpin a new fundamental biological interaction that will have major relevance to normal as well as disease states in our bodies.